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Ethoxylated hydrogenated castor oil

CAS No. 61788-85-0

Ethoxylated hydrogenated castor oil ( PEG-40 hydrogenated castor oil; Macrogolglycerol hydroxystearate; Castor oil, hydrogenated, polyethoxylated )

Catalog No. M28857 CAS No. 61788-85-0

Ethoxylated hydrogenated castor oil is a combination of synthetic polyethylene glycol (PEG) with natural castor oil.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1G 38 In Stock

Biological Information

  • Product Name
    Ethoxylated hydrogenated castor oil
  • Note
    Research use only, not for human use.
  • Brief Description
    Ethoxylated hydrogenated castor oil is a combination of synthetic polyethylene glycol (PEG) with natural castor oil.
  • Description
    Ethoxylated hydrogenated castor oil is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions.(In Vivo):Nearly 20% of Ethoxylated hydrogenated castor oil was used to emulsify the glyceryl monooleate (GMO) as an oil to the aqueous phase. In Webster mice, 5000 mg/kg blank nanoemulsion is given orally to mice once a day for 14 days, this nanoemulsion does not produce hazardous effects, and it has no effect on food intake. 20% Ethoxylated hydrogenated castor oil (10 μl) is applied to the left ear of the mouse, and the right ear served as a control. The mice are observed for development of erthyma for 6 days, no signs of irritation are observed in the mice. Ethoxylated hydrogenated castor oil (injection via the tail vein; 300, 900, and 2700 mg/kg; 4 weeks) is administared for short-term toxicity. At doses of 300 and 900 mg/kg PEG-40 Hydrogenated Castor Oi exhibits no systemic toxicity. However, at a dose of 2700 mg/kg, slight ataxia is observed and body weight is reduced significantly in the males and slightly in the females.
  • Synonyms
    PEG-40 hydrogenated castor oil; Macrogolglycerol hydroxystearate; Castor oil, hydrogenated, polyethoxylated
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    RORγ
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    61788-85-0
  • Formula Weight
    ——
  • Molecular Formula
    ——
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Zhang Y, et al. Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable RORγ Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer. J Med Chem. 2019 May 9;62(9):4716-4730.
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